MEGADETH's DAVE MUSTAINE Opens Up About His Battle With Hand Condition Known As Dupuytren's Contracture

December 24, 2025

In a new interview with Spain's MariskalRockTV, MEGADETH leader Dave Mustaine was asked if he remembers the day that he decided it was time to announce the final round of his career. Mustaine responded (as transcribed by BLABBERMOUTH.NET): "No. No, 'cause I just brought it up. I didn't decide. We were working in the studio [on MEGADETH's upcoming self-titled album], and it just had been a really difficult few weeks. We were trying to get everything done, and it obviously was important to us to make sure that the record was done right. And we had a bunch of deadlines we ran up against that was making it hard and stuff like that. And my hands were hurting really bad. And then I just said one day to my management, 'You know, I don't know how much longer I'm gonna be able to do this.' I didn't say, 'Hey, I wanna retire right now.'"

Elaborating on the issue with his hands which is preventing him from playing his guitar at a hundred percent, Mustaine said: "Yeah, you can look right here on this hand. There's a line right there that's sticking up. That's something called Dupuytren's contracture, and it's gonna make my finger come down like this. It's already started, where it's kind of bunching up a little bit. And then if you look at the tips of my fingers, they're severely arthritic. So, all those bumps makes it really painful to play."

Asked if he has contemplated undergoing surgery to correct the issue or if he has already done that, Dave said: "I'm gonna wait for that until I'm ready to try it, because if I try it now and I'm 95 percent, and I do a surgery and it sets me back, that would've been a bad decision. If I wait until my hands are causing a problem and I try it and it doesn't work, well then I've toured everywhere, I've said farewell to everybody and I'm not leaving stuff unsaid or unfinished."

According to the Mayo Clinic, Dupuytren contracture is a condition that causes one or more fingers to bend toward the palm of the hand. The affected fingers can't straighten completely.

There's no cure for Dupuytren contracture. Treatments can relieve symptoms and slow how quickly the condition gets worse.

Earlier this month, Mustaine spoke to SiriusXM's "Trunk Nation With Eddie Trunk" about MEGADETH's recently announced "farewell" tour, which will officially launch in 2026. The trek, dubbed the "This Was Our Life" tour, will be in support of MEGADETH's upcoming "final", self-titled album, which will arrive in January, and will mark the end of more than four decades of musical history for the 64-year-old musician.

Asked why "Megadeth" will be the band's final album and why he decided to embark on a "farewell" tour at this point of his career, Mustaine said: "It had been a long time coming — just physical stuff that was going on with my hands… My hands were letting me down. And there were other things that were difficult because of all the stuff going on in my neck and my trunk. All that area there has arthritis and it has discs that are bulging. I've got a broken lumbar bone. Of course, you know I have my back fused, up by my shoulders, by my neck. And just a lot of stuff."

Mustaine continued: "I always said when it got to the point where I was unable to give a hundred percent every night, that's when I was gonna start considering winding down. And it wasn't that I was unable to give a hundred percent, because we finished the record, and I think we did a good job on it, but there was a period when we were working and I said to my manager, I said, 'I don't know how much longer I can do this. My hands are really hurting.' And I didn't mean to set the ball rolling. Honestly, I just was making conversation, and it turned into me talking to the band guys and sleeping on it and talking to my family and praying on it. And the answer was clear to me that by the time we're done with the record, I'm gonna know how the record's gonna do. If the record does really well, then I'll be able to have one last really good tour. And the part about the farewell thing, it's kind of like the same thing, isn't it? We've got some dates that we wanna play to say goodbye to our friends."

Dave added: "The thing is we're an American band, but we play everywhere. So it's not like we just are weekend warriors, like country acts here in the States. We've got a lot of touring to do in order to do our farewell properly."

After host Eddie Trunk noted that a lot of veteran artists overstay their welcome and don't gracefully bow out of the music scene after they are no longer able to perform their songs properly, Mustaine concurred.  "I don't think there's any reason [for us] to [keep playing when we are not able to deliver a hundred percent]," he said. "I mean, unless you're financially in a bad way and you need to keep playing, which, by the grace of God, I've been successful. I've been able to pay all my bills. All the band guys, they all get their paychecks on time. We do everything right by the book. So, some people, like I said, they may have to keep playing, because there's nothing else for them to do. Now, when I think about, what am I gonna do after I hang the guitar up, that's in relation to touring, and I believe that I'm going to keep doing music in some way, shape or form. But not in the fashion that I was doing with MEGS because if I can't do it and I need to stop playing with my first love, I'm not gonna go out and try and do it again with someone else."

Last month, Mustaine told Kerrang! magazine that MEGADETH's farewell run of shows could last a long time. "We're easily talking about touring for another three to five years," Dave said. "And if we're going to be doing it for that long then, shit, I'll be looking at the birthday I don't even want to think about," he added, referencing the fact that he will turn 70 in 2031.

As someone who overcame addiction to drugs and alcohol and beat throat cancer, Mustaine added: "I'm not caught up in longevity and stuff like that, and being one of those guys who can play until he's in his 80s. I have to remember that people live and they die. And I need to take good care of myself."

"Megadeth" will be released on January 23, 2026. The follow-up to 2022's "The Sick, The Dying… And The Dead!" will be made available via Mustaine's Tradecraft imprint on Frontiers Label Group's new BLKIIBLK label.

In a press release announcing MEGADETH's final album and farewell tour, Mustaine thanked fans for their commitment and love while celebrating the band's impact on the music world.

"There's so many musicians that have come to the end of their career, whether accidental or intentional," Mustaine said. "Most of them don't get to go out on their own terms on top, and that's where I'm at in my life right now. I have traveled the world and have made millions upon millions of fans and the hardest part of all of this is saying goodbye to them."

He continued. "We can't wait for you to hear this album and see us on tour. If there was ever a perfect time for us to put out a new album, it's now. If there was ever a perfect time to tour the world, it's now. This is also a perfect time for us to tell you that it's our last studio album. We've made a lot of friends over the years and I hope to see all of you on our global farewell tour.

"Don't be mad, don't be sad, be happy for us all, come celebrate with me these next few years. We have done something together that's truly wonderful and will probably never happen again. We started a musical style, we started a revolution, we changed the guitar world and how it's played, and we changed the world. The bands I played in have influenced the world. I love you all for it. Thank you for everything."

For its final album, MEGADETH once again worked with Chris Rakestraw, a producer, mixer and engineer who previously worked on MEGADETH's last two LPs, the aforementioned "The Sick, The Dying... And The Dead!" and 2016's "Dystopia".

Guitarist Teemu Mäntysaari joined MEGADETH two years ago. He stepped in as the replacement for Brazilian-born guitarist Kiko Loureiro, who announced in September 2023 that he would sit out the next leg of MEGADETH's "Crush The World" tour in order to stay home with his children back in Finland. It was later revealed that the now-38-year-old Finnish musician would continue to play guitar for MEGADETH for the foreseeable future, with Loureiro seemingly having no plans to return.

Mäntysaari was born in Tampere, Finland and began playing guitar at the age of 12. In 2004, he joined the band WINTERSUN. He has also been a member of SMACKBOUND since 2015.

In addition to Mustaine and Mäntysaari, MEGADETH's current lineup includes drummer Dirk Verbeuren and bassist James LoMenzo.

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